Heterocyclic modulators of nuclear receptors

Compounds, compositions and methods for modulating the activity of nuclear receptors are provided. In particular, heterocyclic compounds are provided for modulating the activity of farnesoid X receptor (FXR), liver X receptor (LXR) and/or orphan nuclear receptors. In certain embodiments, the compoun...

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Main Authors Martin, Richard, Flatt, Brenton T, Kahl, Jeffrey D, Wang, Tie-Lin
Format Patent
LanguageEnglish
Published 03.10.2006
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Summary:Compounds, compositions and methods for modulating the activity of nuclear receptors are provided. In particular, heterocyclic compounds are provided for modulating the activity of farnesoid X receptor (FXR), liver X receptor (LXR) and/or orphan nuclear receptors. In certain embodiments, the compounds are thiazolidinone derivatives.