Composition comprising pharmaceutical/nutraceutical agent and a bio-enhancer obtained from

The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside 'glycyrrhizin' as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the...

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Main Authors Khanuja, Suman Preet Singh, Kumar, Sushil, Arya, Jai Shankar, Shasany, Ajit Kumar, Singh, Monika, Awasthi, Soumya, Gupta, Subhas Chandra, Darokar, Mahendra Pandurang, Rahman, Laiq Ur
Format Patent
LanguageEnglish
Published 27.12.2005
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Summary:The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside 'glycyrrhizin' as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.