6,7-Oxygenated steroids and uses related thereto

Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stere...

Full description

Saved in:
Bibliographic Details
Main Authors Burgoyne, David L, Shen, Yaping, Langlands, John M, Rogers, Christine, Chau, Joseph H.-L, Piers, Edward, Salari, Hassan
Format Patent
LanguageEnglish
Published 27.09.2005
Online AccessGet full text

Cover

More Information
Summary:Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stereochemistries such as 6α and 7β oxygen substitution, and an alpha hydrogen at the 5 position in addition to having 6α and 7β oxygen substitution. Steroids having 3,4-epoxy functionality are also disclosed. In addition, steroids having C17 pyran and δ-lactone functionality, with oxygen substitution at C6 and C7, or at C15, of the steroid nucleus, are disclosed.