Compositions and methods of diagnosing, monitoring, staging, imaging and treating mammary gland cancer
This invention relates, in part, to newly identified polynucleotides and polypeptides encoded thereby, as well as methods for producing and using these polynucleotides and polypeptides. Antibodies which are immunospecific for these polypeptides are also described. Expression of the newly identified...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
07.09.2004
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| Online Access | Get full text |
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| Summary: | This invention relates, in part, to newly identified polynucleotides and polypeptides encoded thereby, as well as methods for producing and using these polynucleotides and polypeptides. Antibodies which are immunospecific for these polypeptides are also described. Expression of the newly identified polynucleotides and levels of the polypeptides encoded thereby are upregulated in or specific to mammary gland cancer tissue. These new polynucleotides and polypeptides, referred to herein as Mammary Gland Cancer Specific Genes or MSGs are believed to be useful in assays for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating cancers, particularly mammary gland cancer.
The present invention provides polynucleotides and polypeptides which are diagnostic markers for mammary gland cancer. In addition, antibodies immunospecific for these markers are provided. Vectors, hosts cells and methods for producing these markers, as well as methods and tools for using these markers in detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating mammary gland cancer are also provided. |
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