Genotyping by mass spectrometric analysis of allelic fragments
The present invention relates generally to organic chemistry, analytical chemistry, biochemistry, molecular biology, genetics, diagnostics and medicine. In particular, it relates to methods for genotyping diploid cells or organisms by comparing the masses of fragments of alleles that include the pol...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
17.08.2004
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| Online Access | Get full text |
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| Summary: | The present invention relates generally to organic chemistry, analytical chemistry, biochemistry, molecular biology, genetics, diagnostics and medicine. In particular, it relates to methods for genotyping diploid cells or organisms by comparing the masses of fragments of alleles that include the polymorphic locus.
The present invention relates to a method for genotyping a diploid organism by cleaving segments of two alleles such that 7-20 nucleotide fragments that contain a suspected polymorphic locus are produced and comparing the masses of those fragments. |
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