Chymase inhibitor for the treatment of eosinophilia

The present invention relates to a medicament for the prevention or treatment of a disease accompanied with an increase in eosinophils, a pharmaceutical composition for the prevention or treatment of allergic diseases, and a medicament for suppressing an increase in eosinophils. A chymase inhibitor...

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Bibliographic Details
Main Authors Fukami, Harukazu, Watanabe, Naohiro
Format Patent
LanguageEnglish
Published 13.01.2004
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Summary:The present invention relates to a medicament for the prevention or treatment of a disease accompanied with an increase in eosinophils, a pharmaceutical composition for the prevention or treatment of allergic diseases, and a medicament for suppressing an increase in eosinophils. A chymase inhibitor for the prevention or treatment of diseases involving an increase of eosinophils, as the effective ingredient, is disclosed, suppress the progress of the disease and to prevent progression of complications, wherein the chymase inhibitor is a quinazoline derivative having the formula (I): wherein X, R, Rand Rare herein defined, or a pharmaceutically acceptable salt thereof.