Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis

1. Field of the Invention Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful fo...

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Bibliographic Details
Main Authors Johnson Jr., Theodore O, Hua, Ye, Luu, Hiep T, Dragovich, Peter S
Format Patent
LanguageEnglish
Published 26.08.2003
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Summary:1. Field of the Invention Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described.