Method for analyzing polynucleotides

The present invention relates generally to organic chemistry, analytical chemistry, biochemistry, molecular biology, genetics, diagnostics and medicine. In particular, it relates to a method for analyzing polynucleotides; i.e., for determining the complete nucleotide sequence of a polynucleotide, fo...

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Bibliographic Details
Main Authors Stanton, Jr., Vincent P, Wolfe, Jia Liu, Kawate, Tomohiko, Verdine, Gregory L
Format Patent
LanguageEnglish
Published 24.06.2003
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Summary:The present invention relates generally to organic chemistry, analytical chemistry, biochemistry, molecular biology, genetics, diagnostics and medicine. In particular, it relates to a method for analyzing polynucleotides; i.e., for determining the complete nucleotide sequence of a polynucleotide, for detecting variance in the nucleotide sequence between related polynucleotides and for genotyping DNA. The present invention relates to a method of synthesizing a polynucleotide with incorporation of a modified nucleotide.