Therapeutic composition and methods

This application claims priority of invention under 35 U.S.C. §119 from Russian Patent Number 2129867 filed Jun. 10, 1998, and allowed May 10, 1999. The invention provides composition comprising, 1) polyprenol monophosphates of the formula H-[-CH2-C(CH3) CH-CH2]n-O-P( O)(OH)2 wherein n is an integer...

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Main Authors Danilov, Leonid L, Deeva, Anna V, Kuritz, Tanya, Maltsev, Sergei D, Narovlianskiy, Alexander N, Pronin, Alexander V, Sanin, Alexander V, Sosnovskaya, Olga Y, Ozherelkov, Sergei V
Format Patent
LanguageEnglish
Published 25.02.2003
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Summary:This application claims priority of invention under 35 U.S.C. §119 from Russian Patent Number 2129867 filed Jun. 10, 1998, and allowed May 10, 1999. The invention provides composition comprising, 1) polyprenol monophosphates of the formula H-[-CH2-C(CH3) CH-CH2]n-O-P( O)(OH)2 wherein n is an integer from 6-19 inclusive or a salt thereof, and 2) polyprenol pyrophosphates of the formula H-[-CH2-C(CH3) CH-CH]-O-P( O)(OH)-O-P( O)(OH)wherein m is an integer from 6-19 inclusive or a salt thereof, which is useful as an antiviral agent, as an immunomodulatory agent, and for treating cancer. The invention also provides pharmaceutical compositions comprising the compositions of the invention as well as therapeutic methods for using the the compositions.