Method for preparing dual virally inactivated immune globulin for intravenous administration
The present invention relates to an integral, multi-step commercial process for the production of intravenously administrable immune globulin containing IgG ( -globulin) as the main ingredient. A process for producing an intravenously-administrable gamma globulin solution substantially free of conta...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
07.01.2003
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| Online Access | Get full text |
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| Summary: | The present invention relates to an integral, multi-step commercial process for the production of intravenously administrable immune globulin containing IgG ( -globulin) as the main ingredient.
A process for producing an intravenously-administrable gamma globulin solution substantially free of contaminating viruses by fractionating an impure gamma globulin solution and then treating the purified gamma globulin, in any order, with a solvent-detergent for viral inactivation and a heat treating for viral inactivation. Thereafter, denatured impurities, residual solvent and aggregate generated by the heat treatment are removed from the gamma globulin. |
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