Oligonucleotides including 2-aminopyridine and 2-pyridone C-nucleoside units

1. Field of the Invention The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonucleotide-based diagn...

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Bibliographic Details
Main Authors Froehler, Brian C, Gutierrez, Arnold J, Matteucci, Mark D
Format Patent
LanguageEnglish
Published 17.12.2002
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Summary:1. Field of the Invention The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonucleotide-based diagnosis and separation through triplex binding.