Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof

The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase: The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against...

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Main Authors Lee, Hyun Il, Koh, Jong Sung, Lee, Jin Ho, Jung, Won Hee, Shin, You Seung, Chung, Hyun Ho, Kim, Jong Hyun, Ro, Seong Gu, Choi, Tae Saeng, Jeong, Shin Wu, Kwak, Tae Hwan, Ahn, In Ae, Kim, Hyun Sung, Lee, Sun Hwa, Kim, Kwi Hwa, Yoo, Jung Kwon
Format Patent
LanguageEnglish
Published 29.10.2002
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Summary:The present invention relates to a novel imidazole derivative represented by the following formula (1) which shows an inhibitory activity against farnesyl transferase: The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, nand Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.