DNA vaccine for protecting an avian against infectious bursal disease virus

This invention provides a vaccine for protecting an avian against an avian pathogen such as Infectious Bursal Disease Virus, Newcastle Disease Virus, or Mycoplasma gallisepticum, which comprises an effective immunizing amount of a vector comprising an isolated nucleic acid encoding Infectious Bursal...

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Bibliographic Details
Main Authors Aboud-Pirak, Esther, Pirak, Michael E, Shaoul, Esther, Monadeev, Limor
Format Patent
LanguageEnglish
Published 22.10.2002
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Summary:This invention provides a vaccine for protecting an avian against an avian pathogen such as Infectious Bursal Disease Virus, Newcastle Disease Virus, or Mycoplasma gallisepticum, which comprises an effective immunizing amount of a vector comprising an isolated nucleic acid encoding Infectious Bursal Disease Virus peptides such as VP1, VP1s1, VP1s2, VP2, VP2S, VP3, VP4, VP4S and VP5, and a suitable carrier. Further, this invention provides a method for enhancing an avian immune response which comprises administering to the avian an effective amount of the vaccine and a method of immunizing an avian comprising administrating to the avian an effective amount of the vaccine. This invention provides a vaccine for protecting an avian species against infectious bursal disease virus which comprises an effective immunizing amount of a vector comprising 1) one or more isolated nucleic acids encoding an infectious bursal disease virus polypeptide; and 2) a suitable carrier and/or adjuvant.