Composition and method for dermal and transdermal administration of a cytokine

The present invention relates to a composition for transdermal administration of a cytokine. The composition includes a conjugate composed of a cytokine and at least one fatty acid moiety covalently attached to the cytokine. A composition for transdermal administration of a cytokine is described. Th...

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Bibliographic Details
Main Authors Foldvari, Marianna, Attah-Poku, Sam Kwadwo
Format Patent
LanguageEnglish
Published 03.09.2002
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Summary:The present invention relates to a composition for transdermal administration of a cytokine. The composition includes a conjugate composed of a cytokine and at least one fatty acid moiety covalently attached to the cytokine. A composition for transdermal administration of a cytokine is described. The composition includes a conjugate composed of a cytokine, such as an interferon, and at least one fatty acid moiety covalently attached to the cytokine. The conjugate has enhanced cutaneous delivery relative to the cytokine alone.