Hydraulic surgical cement

This invention concerns a cement for surgical purposes, a method for producing brushite as temporary bone replacement material, and a temporary bone replacement material. The cement for surgical purposes includes three components. The first component includes beta tertiary calciumphosphate -Ca(PO)(...

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Bibliographic Details
Main Authors Lemaitre, Jacques, Bohner, Marc, Van Landuyt, Pascale
Format Patent
LanguageEnglish
Published 30.07.2002
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Summary:This invention concerns a cement for surgical purposes, a method for producing brushite as temporary bone replacement material, and a temporary bone replacement material. The cement for surgical purposes includes three components. The first component includes beta tertiary calciumphosphate -Ca(PO)( -TCP) particles; and monocalcium phosphate Ca(HPO)(MCPA) or monocalcium phosphate monohydrate Ca(HPO).HO (MCPM) particles or phosphoric acid. The second component includes water. The third component includes particles having an average diameter which is larger than the average diameter of the beta tertiary calciumphosphate -Ca(PO)( -TCP) particles of the first component. Upon mixing of the three components a hardened mass comprising brushite CaHPO.2HO (DCPD) is formed. The -TCP particles have a specific surface area of less than 10,000 m/g and a Ca/P atomic ratio different from 1.50. The component constitutes 1 to 99 volume-percent of the hardened mass. The cements according to the invention may be used in dental and maxillofacial surgery (alveolar ridge reconstruction, dental socket filling), for orthopaedic applications (bone fracture repair, bone augmentation) and for local drug delivery (antibiotics, anti-inflammatory and anti-cancer drugs).