Gene switch

The present invention relates to the identification and characterisation of insect steroid receptors from the Lepidoptera species and the nucleic acid encoding therefor. The present invention also relates to the use of such receptors, and such nucleic acid, particularly, but not exclusively, in scre...

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Bibliographic Details
Main Authors Jepson, Ian, Martinez, Alberto, Greenland, Andrew James
Format Patent
LanguageEnglish
Published 30.04.2002
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Summary:The present invention relates to the identification and characterisation of insect steroid receptors from the Lepidoptera species and the nucleic acid encoding therefor. The present invention also relates to the use of such receptors, and such nucleic acid, particularly, but not exclusively, in screening methods, and gene switches. By gene switch we mean a gene sequence which is responsive to an applied exogenous chemical inducer enabling external control of expression of the gene controlled by said gene sequence. The invention relates to an insect steroid receptor protein which is capable of acting as a gene switch which is responsive to a chemical inducer enabling external control of the gene.