Azole compounds, their production and use
The present invention relates to azole compounds useful as antifungal therapeutic agents, methods for producing the same and use thereof. The present invention provides an azole compound represented by the formula (I): wherein Ar is an optionally substituted phenyl group; Rand R, the same or differe...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
26.03.2002
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| Online Access | Get full text |
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| Summary: | The present invention relates to azole compounds useful as antifungal therapeutic agents, methods for producing the same and use thereof.
The present invention provides an azole compound represented by the formula (I): wherein Ar is an optionally substituted phenyl group; Rand R, the same or different, are a hydrogen atom or a lower alkyl group, or Rand Rmay combine together to form a lower alkylene group; R is a hydrogen atom or an acyl group; X is a nitrogen atom or a methine group; A is Y Z (Y and Z, the same or different, are a nitrogen atom or a methine group optionally substituted with a lower alkyl group) or an ethylene group optionally substituted with a lower alkyl group; n is an integer from 0 to 2; and Az is an optionally substituted azolyl group, or its salt, which is useful for a prevention and therapy of a fungal infection of a mammal as a antifungal agent. |
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