DocosahexAenoic acid as retinoid X-receptor ligand and uses thereof

This invention relates to the retinoid X receptor, referred to hereafter as "RXR." More particularly, it relates to the identification of its ligands, and the ramifications of this identification. This invention involves the identification of a ligand for the retinol X receptor. Specifical...

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Bibliographic Details
Main Authors de Urquiza, Alexander Mata, Perlmann, Thomas, Sjöberg, Maria, Suya, Liu, Sjövall, Jan, Griffiths, William, Zetterstrom, Rolf
Format Patent
LanguageEnglish
Published 12.03.2002
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Summary:This invention relates to the retinoid X receptor, referred to hereafter as "RXR." More particularly, it relates to the identification of its ligands, and the ramifications of this identification. This invention involves the identification of a ligand for the retinol X receptor. Specifically docosahexaenoic has been identified as an RXR ligand. Various assays based upon this observation are a feature of this invention.