Crystal modification of torasemide

The present invention relates to the characterization of a new crystal modification III of torasemide, to a process for the preparation thereof by the use of controlled acidifying of alkaline solutions of torasemide with inorganic or organic acids with or without addition of a crystal seed, to its u...

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Bibliographic Details
Main Authors Dumic, Miljenko, Filic, Darko, Danilovski, Aleksandar, Klepic, Bozena, Fistric, Ines, Oresic, Marina, Mikulcic, Jasna
Format Patent
LanguageEnglish
Published 18.11.2004
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Summary:The present invention relates to the characterization of a new crystal modification III of torasemide, to a process for the preparation thereof by the use of controlled acidifying of alkaline solutions of torasemide with inorganic or organic acids with or without addition of a crystal seed, to its use as a raw material for the preparation of the crystal modification I of torasemide and of pharmaceutically acceptable salts of torasemide as well as to pharmaceutical forms containing this new crystal modification III of torasemide.