Parp inhibitors

The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: 1 or a pharmaceutica...

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Main Authors Beaton, Graham, Moree, Wilna, Rueter, Jaimie, Dahl, Russell, McElligott, David, Goldman, Phyllis, Demaggio, Anthony, Christenson, Erik, Herendeen, Dan, Fowler, Kerry, Huang, Danwen, Bertino, Jaimie, Bourdon, Lisa, Fairfax, David, Jiang, Qin, Reisch, Helge, Song, Ren, Zhichkin, Pavel
Format Patent
LanguageEnglish
Published 06.05.2004
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Summary:The present invention provides compounds comprising a bicyclic aryl moiety, such as 2H-phthalazin-1-one or derivatives thereof, compositions comprising the same, and methods for producing and using the same. In particular, the present invention provides compounds of the formula: 1 or a pharmaceutically acceptable salt, a hydrate, a solvate, or a prodrug thereof; where Q 1 , Q 2 and Y are those defined herein.