Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polyn...

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Main Authors Alsobrook, John, Anderson, David, Boldog, Ferenc, Burgess, Catherine, Chillakuru, Rajeev, Edinger, Shlomit, Gerlach, Valerie, Gorman, Linda, Gould-Rothberg, Bonnie, Guo, Xiaojia, Jeffers, Michael, Ji, Weizhen, Li, Li, Malyankar, Uriel, Miller, Charles, Murphey, Ryan, Patturajan, Meera, Peyman, John, Rastelli, Luca, Rieger, Daniel, Shenoy, Suresh, Smithson, Glennda, Starling, Gary, Taupier, Raymond, Voss, Edward, Zhong, Haihong, Zhong, Mei
Format Patent
LanguageEnglish
Published 05.02.2004
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Summary:Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.