Solid supports having surface-treated layer formed thereon

For the purpose of overcoming a conventional art problem of spot detachment during the process of gene analysis (for example, hybridization) by strongly immobilizing biological material samples such as DNA or protein via covalent bonding on a substrate, the invention provides a solid support with a...

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Bibliographic Details
Main Authors Tanga, Michifumi, Okayama, Hironao, Okamura, Hiroshi, Ehara, Keigo, Takagi, Kenichi
Format Patent
LanguageEnglish
Published 22.01.2004
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Summary:For the purpose of overcoming a conventional art problem of spot detachment during the process of gene analysis (for example, hybridization) by strongly immobilizing biological material samples such as DNA or protein via covalent bonding on a substrate, the invention provides a solid support with a surface-treated layer of hafnium carbide, niob carbide, silicone carbide, tantalum carbide, thorium carbide, titanium carbide, uranium carbide, tungsten carbide or zirconium carbide as formed on the surface thereof so as to enable the immobilization of oligonucleotide or DNA fragment on the surface thereof; a solid support immobilizing oligonucleotide or DNA fragment on the film of the surface-treated layer; and a method for analyzing gene by immobilizing gene on the surface of such solid support.