Antibodies to OCIF-binding molecules

A novel protein which binds to Osteoclastogenesis Inhibitory Factor (OCIF-binding molecule; OBM), a process for preparing the same, DNA encoding said protein, a protein having an amino acid sequence encoded by this DNA, a method for producing said protein by genetic engineering technique, and a phar...

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Main Authors Yamaguchi, Kyoji, Yasuda, Hisataka, Nakagawa, Nobuaki, Shima, Nobuyuki, Kinosaki, Masahiko, Tsuda, Eisuke, Goto, Masaaki, Yano, Kazuki, Tomoyasu, Akihiro, Kobayashi, Fumie, Washida, Naohiro, Takahashi, Ken, Morinaga, Tomonori, Higashio, Kanji
Format Patent
LanguageEnglish
Published 18.09.2003
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Summary:A novel protein which binds to Osteoclastogenesis Inhibitory Factor (OCIF-binding molecule; OBM), a process for preparing the same, DNA encoding said protein, a protein having an amino acid sequence encoded by this DNA, a method for producing said protein by genetic engineering technique, and a pharmaceutical composition containing said protein. Screening methods for a substance for controlling expression of said protein using said protein and the DNA, a substance which inhibits or modulates the biological activity of said protein, or a receptor which transmits the action of said protein through binding to said protein, the substance obtained by the screening methods, and a pharmaceutical composition which contains this substance. An antibody for said protein, a process for preparing the same, a measuring method of said protein using the antibody, and a medicine comprising this antibody.