Novel carbapenem derivatives

Disclosed is a novel carbapenem derivative having a substituted imidazo[5,1-b]thiazole group at the 2-position on the, carbapenem ring have high anti-microbial activities against -lactamase producing bacteria, MRSA, resistant- Pseudomonas aeruginosa , PRSP, enterococci, and influenza, and high stabi...

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Main Authors Sasaki, Toshiro, Kano, Yuko, Sambongi, Yumiko, Tanabe, Kiyoshi, Akiyama, Yoshihisa, Kitagawa, Hideo, Maruyama, Takahisa, Takizawa, Hiromasa, Ando, Takashi, Aihara, Kazuhiro, Atsumi, Kunio, Iwamatsu, Katsuyoshi, Ida, Takashi
Format Patent
LanguageEnglish
Published 07.08.2003
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Summary:Disclosed is a novel carbapenem derivative having a substituted imidazo[5,1-b]thiazole group at the 2-position on the, carbapenem ring have high anti-microbial activities against -lactamase producing bacteria, MRSA, resistant- Pseudomonas aeruginosa , PRSP, enterococci, and influenza, and high stabilities to DHP-1. According to the present invention, there is provided a compound represented by the formula (I), or a pharmacologically acceptable salt thereof or an ester at the 3-position on the carbapenem ring thereof: 1