7-substituted tetracycline compounds

The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tet...

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Main Authors Frechette, Roger, Nelson, Mark, Viski, Peter, Ismail, Mohamed, Bowser, Todd, Bhatia, Beena, Messersmith, David, McIntyre, Laura, Koza, Darrell, Rennie, Glen, Sheahan, Paul, Hawkins, Paul, Verma, Atul, Warchol, Tadeusz, Bandarage, Upul
Format Patent
LanguageEnglish
Published 20.03.2003
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Summary:The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.