DEXTRAN REDUCED IN BORON CONTENT, PROCESS FOR PRODUCING THE SAME, AND DEXTRAN PACKED IS CONTAINER IN SOLUTION STATE

The present invention relates to dextran whose boron content is reduced to a value less than 0.30 g/g (dry basis) calculated on the basis of boron atom, a process for producing the same, and dextran with which a container is filled in a solution state. Dextran of the present invention is obtained by...

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Bibliographic Details
Main Authors MACHIDA, HARUO, KATO, SHIGEAKI, HIRATA, YUUKI, AOKI, MITSUO, KOBATAKE, HIDEKI
Format Patent
LanguageEnglish
Published 23.01.2003
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Summary:The present invention relates to dextran whose boron content is reduced to a value less than 0.30 g/g (dry basis) calculated on the basis of boron atom, a process for producing the same, and dextran with which a container is filled in a solution state. Dextran of the present invention is obtained by treating a boron-containing dextran with a lower alcohol, and said dextran has such a characteristic that deposition is inhibited or the deposition rate is drastically reduced when using it in the form of a solution. Therefore, an isotonic sodium chloride solution of said dextran is suitably used as substitute plasma or external perfusate in an operation.