Bottle-brush type coatings with entangled hydrophilic polymer
The invention relates to a process for coating a material surface comprising the steps of: (a) providing an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization; (b) graft polymerizing a hydrophilic ethylenically unsaturated macromon...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
09.01.2003
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| Online Access | Get full text |
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| Summary: | The invention relates to a process for coating a material surface comprising the steps of:
(a) providing an inorganic or organic bulk material having covalently bound to its surface initiator moieties for radical polymerization;
(b) graft polymerizing a hydrophilic ethylenically unsaturated macromonomer from the bulk material surface in the presence of a biocompatible hydrophilic polymer being devoid of polymerizable ethylenically unsaturated groups and thereby entrapping said hydrophilic polymer within the polymer matrix formed by the polymerization of the macromonomer.
Composite materials obtainable according to the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices. |
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