New 4-arylpiperidine derivatives for the treatment of pruritus

There is provided a compound of formula I, 1 wherein Het 1 , R 1 , R 2 , R 3 , X and n have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.

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Bibliographic Details
Main Authors Gibson, Stephen, Tommasini, Ivan, Verrier, Kimberley, Dutton, Christopher, Gethin, David, Critcher, Douglas, Armer, Richard
Format Patent
LanguageEnglish
Published 02.01.2003
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Summary:There is provided a compound of formula I, 1 wherein Het 1 , R 1 , R 2 , R 3 , X and n have meanings given in the description, which are useful in the prophylaxis and in the treatment of diseases mediated by opiate receptors, such as pruritus.