Triterpene derivatives and remedies for liver diseases

A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: 1 wherein R 1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alk...

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Bibliographic Details
Main Authors Sasaki, Kazue, Minowa, Nobuto, Nishiyama, Shoji, Kuzuhara, Hiroyuki
Format Patent
LanguageEnglish
Published 07.02.2002
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Summary:A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof: 1 wherein R 1 represents a hydroxyl group, arylmethyloxy, lower alkoxy, or lower alkanoyloxy, R 2 represents lower alkyl, lower alkenyl, -CH 2 OR 5 , formyl, -COOR 6 , or -CH 2 N(R 7 )R 8 , or R 1 and R 2 may combine with each other to form -O-C(R 9 )R 10 -O-CH 2 -, R 3 and R 4 , which may be the same or different represent a hydrogen atom, a hydroxyl group, lower alkyl, lower alkenyl, aryl, hydroxymethyl, -N(R 11 )R 12 , formyl, -COOR 6 , or -OR 13 , or R 3 and R 4 may combine with each other to form oxo, hydroxyimino, or alkylidene and X represents O, CH 2 , or NH.