HPV-SPECIFIC OLIGONUCLEOTIDES

The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E 1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expr...

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Main Authors FRANK, BRUCE L, ROBERT, PETER C, SZYMKOWSKI, DAVID E, MILLS, JOHN S, GOODCHILD, JOHN, WOLFE, JIA L, KILKUSKIE, ROBERT E, GREENFIELD, ISOBEL M, SULLIVAN, VERONIA
Format Patent
LanguageEnglish
Published 02.08.2001
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Summary:The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E 1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.