Pseudoleukocytosis and pseudothrombocytosis in cryoglobulinemia

Cryoglobulinemia has been rarely reported to cause false elevation in platelet and/or leukocyte counts due to temperature-dependent protein precipitates that interpreted as blood cells at room temperature. Upon heating to 37°C, these blood counts decrease to normal levels as cryoproteins dissolve. H...

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Published inTurkish journal of medical sciences Vol. 28; no. 3; pp. 299 - 302
Main Authors MÜFTÜOĞLU, Osman, DEMİROĞLU, Haluk, DÜNDAR, Semra, KARAAHMETOĞLU, Selma, BÜYÜKAŞIK, Yahya, İLERİ, Naciye Şemnur
Format Journal Article
LanguageEnglish
Published TÜBİTAK 1998
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Summary:Cryoglobulinemia has been rarely reported to cause false elevation in platelet and/or leukocyte counts due to temperature-dependent protein precipitates that interpreted as blood cells at room temperature. Upon heating to 37°C, these blood counts decrease to normal levels as cryoproteins dissolve. Here, we report two cases with this rare phenomenon that may lead to inappropriate investigations in clinical practice and have diagnostic significance when kept in mind.
Bibliography:TTIP
ISSN:1300-0144