Severe lymphopenia in tuberculosis (A mere coincidence or a significant association?)

A variety of infectious agents can cause secondary immunodeficient states. We herein present a one-year-old patient, admitted to the hospital with severe lymphopenia, who was subsequently diagnosed as tuberculosis. After the antituberculosis (anti TB) therapy was started, the clinical condition and...

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Bibliographic Details
Published inTurkish journal of pediatrics Vol. 42; no. 1; pp. 65 - 67
Main Authors GÖÇMEN, Ayhan, ÖZEN, Seza, ZAFER, Yeşim, TEZCAN, İlhan, GÖNÇ, E. Nazlı
Format Journal Article
LanguageEnglish
Published Türk Pediatri Derneği 2000
Subjects
Bacterial infections and mycoses
Bakteriyel enfeksiyonlar ve mikozlar
Child
Childhood
Hemic and lymphatic diseases
Hemik ve lenfatik hastalıklar
Lenfopeni
Lymphopenia
Mycobacterium tuberculosis
Polimeraz zincir reaksiyonu
Polymerase Chain Reaction
Tuberculosis
Tüberküloz
Çocuk
Çocukluk çağı
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Summary:A variety of infectious agents can cause secondary immunodeficient states. We herein present a one-year-old patient, admitted to the hospital with severe lymphopenia, who was subsequently diagnosed as tuberculosis. After the antituberculosis (anti TB) therapy was started, the clinical condition and the immunologic findings of the patient improved. We have thus concluded that the transient lymphopenia of the patient was due to Mycobacterium tuberculosis. We suggest that immunodeficiency should be investigated more often in children with tuberculosis and that further studies will shed light on the pathogenesis of this aspect of the disease.
Bibliography:TTIP
ISSN:0041-4301