Wrinkled Surfaces Designed for Biorelated Applications

• Published in: Wrinkled Polymer Surfaces pp. 273 - 290
• Main Authors: González-Henríquez, C. M., Sarabia Vallejos, M. A., Rodríguez-Hernández, Juan
• Format: Book Chapter
• Language: English
• Published: Cham Springer International Publishing
• Subjects: Antibiofouling; Biocompatible devices; Cell proliferation; Cellular alignment or differentiation; Wrinkled polymer surfaces
• ISBN: 3030051226; 9783030051228
• DOI: 10.1007/978-3-030-05123-5_12

Wrinkling and buckling of multilayered materials are common methodologies used for generating micro- or nano-patterned topographies on the top of the devices. According to the material used and the size and distribution of those patterns, some of these devices can be used for several interesting purposes like aeronautics, force/pressure sensing, or particle selective transport. Biorelated purposes is also a field of application which has attracted high interest in the last years. To take advantage of micro-pattern characteristics is a clever way to impart some interesting capabilities to the material. Interestingly, these modifications could generate or improve some useful properties like biocompatibility or antibiofouling capacities. In this chapter, some of the most relevant examples of biorelated applications of wrinkled patterns are fully reviewed. As a summary, different topics are mentioned in this section, like scaffolds with cell proliferation improvement, devices which allow cellular alignment or differentiation, surfaces which help in the generation of multicellular-spheroid structures, or antibiofouling surfaces.