Escala “Pediatric Index Mortality 3” (PIM3) como predictor de mortalidad en unidades de cuidado intensivo pediátrico ubicadas a gran altitud
Resumen: El Pediatric Index of Mortality 3 (PIM3) es una escala que estima el riesgo de mortalidad en niños ingresados a Unidad de Cuidado Intensivo Pediátrico (UCIP) en la primera hora del ingreso. Objetivo: validar la escala PIM3 en población pediátrica que ingresa a UCIP en alturas sobre los 2.50...
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Published in | Andes pediatrica : revista Chilena de pediatría |
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Abstract | Resumen: El Pediatric Index of Mortality 3 (PIM3) es una escala que estima el riesgo de mortalidad en niños ingresados a Unidad de Cuidado Intensivo Pediátrico (UCIP) en la primera hora del ingreso. Objetivo: validar la escala PIM3 en población pediátrica que ingresa a UCIP en alturas sobre los 2.500 metros sobre el nivel del mar (m.s.n.m.), y evaluar si el lactato y el índice Saturación de Oxígeno/Fracción inspirada de oxígeno (SpO2/FiO2) mejoran su capacidad de predicción de mortalidad. Pacientes y Método: Estudio prospectivo multicéntrico realizado en diez UCIP de Colombia entre noviembre de 2016 y junio de 2017. Se recolectaron variables para cálculo del PIM3, lactato sérico y el índice SpO2/FiO2. Se validó su capacidad de discriminación con el área bajo la curva ROC y la calibración mediante la prueba de bondad de ajuste de Hosmer Lemeshow. Resultados: Se incluyeron 2.803 registros de admisiones, con una mortalidad global de 4,8%, y razón estandarizada de mortalidad de 1,1 (IC95%; 1,00-1,3). El PIM3 mostró una baja calibración (p < 0,001) y una adecuada discriminación para la población aplicada (ROC 0,84; IC95% 0,83-0,86). La adición de lactato sérico y SpO2/ FiO2 permitieron una buena calibración (p = 0,75), y mantuvo una alta discriminación de mortalidad (ROC 0,86; IC95% 0,84-0,87). Conclusiones: El comportamiento de la escala PIM3 tiene adecuada discriminación, pero una baja calibración en niños admitidos a UCIP sobre los 2500 m.s.n.m.. Las variables lactato y SpO2/FiO2 mejoraron su habilidad predictiva. |
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AbstractList | Resumen: El Pediatric Index of Mortality 3 (PIM3) es una escala que estima el riesgo de mortalidad en niños ingresados a Unidad de Cuidado Intensivo Pediátrico (UCIP) en la primera hora del ingreso. Objetivo: validar la escala PIM3 en población pediátrica que ingresa a UCIP en alturas sobre los 2.500 metros sobre el nivel del mar (m.s.n.m.), y evaluar si el lactato y el índice Saturación de Oxígeno/Fracción inspirada de oxígeno (SpO2/FiO2) mejoran su capacidad de predicción de mortalidad. Pacientes y Método: Estudio prospectivo multicéntrico realizado en diez UCIP de Colombia entre noviembre de 2016 y junio de 2017. Se recolectaron variables para cálculo del PIM3, lactato sérico y el índice SpO2/FiO2. Se validó su capacidad de discriminación con el área bajo la curva ROC y la calibración mediante la prueba de bondad de ajuste de Hosmer Lemeshow. Resultados: Se incluyeron 2.803 registros de admisiones, con una mortalidad global de 4,8%, y razón estandarizada de mortalidad de 1,1 (IC95%; 1,00-1,3). El PIM3 mostró una baja calibración (p < 0,001) y una adecuada discriminación para la población aplicada (ROC 0,84; IC95% 0,83-0,86). La adición de lactato sérico y SpO2/ FiO2 permitieron una buena calibración (p = 0,75), y mantuvo una alta discriminación de mortalidad (ROC 0,86; IC95% 0,84-0,87). Conclusiones: El comportamiento de la escala PIM3 tiene adecuada discriminación, pero una baja calibración en niños admitidos a UCIP sobre los 2500 m.s.n.m.. Las variables lactato y SpO2/FiO2 mejoraron su habilidad predictiva. |
Author | Godoy, Javier Vasquez Hoyos, Pablo López-Barón, Eliana Fernández-Sarmiento, Jaime Martinez-Solarte, Mario Ramírez, Ivan Perdomo Pardo, Rosalba Godoy, Carol Duitama Vergara, Lorena Maya, Luis Carlos Mejía, Luz Marina González, Otto Izquierdo Borrero, Ledys María Mazzillo, Liliana Roa, Juan David Reyes, Martha |
AuthorAffiliation | Fundación Clínica Shaio Hospital Pablo Tobón Uribe Hospital Militar Central Fundación Hospital Infantil Los Ángeles Hospital de San José Universidad Nacional de Colombia |
AuthorAffiliation_xml | – name: Fundación Clínica Shaio – name: Hospital de San José – name: Fundación Hospital Infantil Los Ángeles – name: Hospital Militar Central – name: Hospital Pablo Tobón Uribe – name: Universidad Nacional de Colombia |
Author_xml | – sequence: 1 givenname: Eliana surname: López-Barón fullname: López-Barón, Eliana organization: Universidad Nacional de Colombia – sequence: 2 givenname: Pablo surname: Vasquez Hoyos fullname: Vasquez Hoyos, Pablo organization: Universidad Nacional de Colombia – sequence: 3 givenname: Mario surname: Martinez-Solarte fullname: Martinez-Solarte, Mario organization: Universidad Nacional de Colombia – sequence: 4 givenname: Javier surname: Godoy fullname: Godoy, Javier organization: Universidad Nacional de Colombia – sequence: 5 givenname: Luis Carlos surname: Maya fullname: Maya, Luis Carlos organization: Universidad Nacional de Colombia – sequence: 6 givenname: Ivan Perdomo surname: Ramírez fullname: Ramírez, Ivan Perdomo organization: Universidad Nacional de Colombia – sequence: 7 givenname: Luz Marina surname: Mejía fullname: Mejía, Luz Marina organization: Universidad Nacional de Colombia – sequence: 8 givenname: Carol surname: Godoy fullname: Godoy, Carol organization: Universidad Nacional de Colombia – sequence: 9 givenname: Rosalba surname: Pardo fullname: Pardo, Rosalba organization: Universidad Nacional de Colombia – sequence: 10 givenname: Juan David surname: Roa fullname: Roa, Juan David organization: Universidad Nacional de Colombia – sequence: 11 givenname: Liliana surname: Mazzillo fullname: Mazzillo, Liliana organization: Fundación Hospital Infantil Los Ángeles – sequence: 12 givenname: Otto surname: González fullname: González, Otto organization: Fundación Clínica Shaio – sequence: 13 givenname: Jaime surname: Fernández-Sarmiento fullname: Fernández-Sarmiento, Jaime organization: Universidad Nacional de Colombia – sequence: 14 givenname: Ledys María surname: Izquierdo Borrero fullname: Izquierdo Borrero, Ledys María organization: Universidad Nacional de Colombia – sequence: 15 givenname: Lorena surname: Duitama Vergara fullname: Duitama Vergara, Lorena organization: Universidad Nacional de Colombia – sequence: 16 givenname: Martha surname: Reyes fullname: Reyes, Martha organization: Universidad Nacional de Colombia |
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Keywords | Pediatrics Intensive Care Units Pediátrica Lactic Acid Critical Illness Mortalidad Infantil Unidades de Cuidados Intensivos Enfermedad Crítica Child Mortality Saturación de Oxígeno Altitud Oxygen Saturation Ácido Láctico Altitude |
Language | Portuguese |
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References | Choudhuri, JA; Ogden, LG; Ruttenber, AJ 2006; 117 Moschovis, PP; Banajeh, S; MacLeod, WB 2013; 132 Solomon, LJ; Naidoo, KD; Appel, I 2021; 22 Wang, Y; Wang, J. 2020; 20 Ray, S; Rogers, L; Pagel, C 2017; 18 Koliski, A; Cat, I; Giraldi, DJ 2005; 81 Bebic, Z; Brooks Peterson, M; Polaner, DM. 2022; 32 Audsley, A; Wallace, RM; Price, MF. 2016; 20 Benaron, DA; Benitz, WE. 1994; 148 Shann, F. 2002; 28 Tyagi, P; Tullu, MS; Agrawal, M. 2018; 7 Giussani, DA; Phillips, PS; Anstee, S 2001; 49 Straney, L; Clements, A; Parslow, RC 2013; 14 Wong, JJ; Hornik, CP; Mok, YH 2018; 47 Bai, Z; Zhu, X; Li, M 2014; 14 Wolfler, A; Osello, R; Gualino, J 2016; 17 Arias López, MDP; Boada, N; Fernández, A 2018; 19 Quiñónez-López, D; Patino-Hernandez, D; Zuluaga, CA 2020; 24 Sari, DSP; Saputra, I; Triratna, S 2017; 57 Niermeyer, S; Andrade Mollinedo, P; Huicho, L. 2009; 94 Morris, KP; Kapetanstrataki, M; Wilkins, B 2022; 23 Villamonte, W; Escalante, D; Yabar, J 2014; 31 Lee, OJ; Jung, M; Kim, M 2017; 32 Chapur, VF; Alfaro, EL; Bronberg, R 2017; 115 Ferguson, ND; Fan, E; Camporota, L 2012; 38 |
References_xml | – volume: 19 start-page: e653 issue: 12 year: 2018 end-page: e661 article-title: Performance of the Pediatric Index of Mortality 3 Score in PICUs in Argentina: A Prospective, National Multicenter Study publication-title: Pediatr Crit Care Med. contributor: fullname: Arias López, MDP; Boada, N; Fernández, A – volume: 94 start-page: 806 issue: 10 year: 2009 end-page: 811 article-title: Child health and living at high altitude publication-title: Arch Dis Child. contributor: fullname: Niermeyer, S; Andrade Mollinedo, P; Huicho, L. – publication-title: Under-five mortality rate (per 1000 live births) (SDG 3.2.1) – volume: 38 start-page: 1573 issue: 10 year: 2012 end-page: 1582 article-title: The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material publication-title: Intensive Care Med. contributor: fullname: Ferguson, ND; Fan, E; Camporota, L – volume: 32 start-page: 118 issue: 2 year: 2022 end-page: 125 article-title: Respiratory physiology at high altitude and considerations for pediatric patients publication-title: Paediatr Anaesth. contributor: fullname: Bebic, Z; Brooks Peterson, M; Polaner, DM. – volume: 7 start-page: 201 issue: 4 year: 2018 end-page: 206 article-title: Comparison of Pediatric Risk of Mortality III, Pediatric Index of Mortality 2, and Pediatric Index of Mortality 3 in Predicting Mortality in a Pediatric Intensive Care Unit publication-title: J Pediatr Intensive Care contributor: fullname: Tyagi, P; Tullu, MS; Agrawal, M. – volume: 117 start-page: 349 issue: 2 year: 2006 end-page: 356 article-title: Effect of altitude on hospitalizations for respiratory syncytial virus infection publication-title: Pediatrics contributor: fullname: Choudhuri, JA; Ogden, LG; Ruttenber, AJ – volume: 115 start-page: 462 issue: 5 year: 2017 end-page: 469 article-title: Relationship between infant mortality and altitude in the Northwest region of Argentina publication-title: Arch Argent Pediatr. contributor: fullname: Chapur, VF; Alfaro, EL; Bronberg, R – volume: 47 start-page: 285 issue: 8 year: 2018 end-page: 290 article-title: Performance of the Paediatric Index of Mortality 3 and Paediatric Logistic Organ Dysfunction 2 Scores in Critically Ill Children publication-title: Ann Acad Med Singap. contributor: fullname: Wong, JJ; Hornik, CP; Mok, YH – volume: 57 start-page: 164 issue: 3 year: 2017 end-page: 170 article-title: The pediatric index of mortality 3 score to predict mortality in a pediatric intensive care unit in Palembang, South Sumatera, Indonesia publication-title: Paediatr Indones. contributor: fullname: Sari, DSP; Saputra, I; Triratna, S – volume: 49 start-page: 490 issue: 4 year: 2001 end-page: 494 article-title: Effects of altitude versus economic status on birth weight and body shape at birth publication-title: Pediatr Res. contributor: fullname: Giussani, DA; Phillips, PS; Anstee, S – volume: 81 start-page: 287 issue: 4 year: 2005 end-page: 292 article-title: Lactato sérico como marcador prognóstico em crianças gravemente doentes [Blood lactate concentration as prognostic marker in critically ill children] publication-title: J Pediatr (Rio J) contributor: fullname: Koliski, A; Cat, I; Giraldi, DJ – volume: 148 start-page: 294 issue: 3 year: 1994 end-page: 300 article-title: Maximizing the stability of oxygen delivered via nasal cannula publication-title: Arch Pediatr Adolesc Med. contributor: fullname: Benaron, DA; Benitz, WE. – volume: 32 start-page: 365 issue: 2 year: 2017 end-page: 370 article-title: Validation of the Pediatric Index of Mortality 3 in a Single Pediatric Intensive Care Unit in Korea publication-title: J Korean Med Sci. contributor: fullname: Lee, OJ; Jung, M; Kim, M – volume: 22 start-page: 813 issue: 9 year: 2021 end-page: 821 article-title: Pediatric Index of Mortality 3-An Evaluation of Function Among ICUs In South Africa publication-title: Pediatr Crit Care Med. contributor: fullname: Solomon, LJ; Naidoo, KD; Appel, I – volume: 24 start-page: 1095 issue: 11 year: 2020 end-page: 1102 article-title: Comparison of Performance of the Pediatric Index of Mortality (PIM)-2 and PIM-3 Scores in the Pediatric Intensive Care Unit of a High Complexity Institution publication-title: Indian J Crit Care Med. contributor: fullname: Quiñónez-López, D; Patino-Hernandez, D; Zuluaga, CA – volume: 14 start-page: 673 issue: 7 year: 2013 end-page: 681 article-title: Paediatric index of mortality 3: an updated model for predicting mortality in pediatric intensive care publication-title: Pediatr Crit Care Med. contributor: fullname: Straney, L; Clements, A; Parslow, RC – volume: 20 start-page: 2415 issue: 12 year: 2016 end-page: 2423 article-title: Mountain Child: Systematic Literature Review publication-title: Matern Child Health J. contributor: fullname: Audsley, A; Wallace, RM; Price, MF. – volume: 23 start-page: e268 issue: 6 year: 2022 end-page: e276 article-title: Lactate, Base Excess, and the Pediatric Index of Mortality: Exploratory Study of an International, Multicenter Dataset publication-title: Pediatr Crit Care Med. contributor: fullname: Morris, KP; Kapetanstrataki, M; Wilkins, B – volume: 132 start-page: e1156 issue: 5 year: 2013 end-page: e1162 article-title: Childhood anemia at high altitude: risk factors for poor outcomes in severe pneumonia publication-title: Pediatrics contributor: fullname: Moschovis, PP; Banajeh, S; MacLeod, WB – volume: 17 start-page: 251 issue: 3 year: 2016 end-page: 256 article-title: The Importance of Mortality Risk Assessment: Validation of the Pediatric Index of Mortality 3 Score publication-title: Pediatr Crit Care Med. contributor: fullname: Wolfler, A; Osello, R; Gualino, J – volume: 14 year: 2014 article-title: Effectiveness of predicting in-hospital mortality in critically ill children by assessing blood lactate levels at admission publication-title: BMC Pediatr. contributor: fullname: Bai, Z; Zhu, X; Li, M – volume: 18 start-page: e131 issue: 3 year: 2017 end-page: e136 article-title: PaO2/FIO2 Ratio Derived From the SpO2/FIO2 Ratio to Improve Mortality Prediction Using the Pediatric Index of Mortality-3 Score in Transported Intensive Care Admissions publication-title: Pediatr Crit Care Med. contributor: fullname: Ray, S; Rogers, L; Pagel, C – volume: 20 start-page: 822 issue: 1 year: 2020 end-page: 822 article-title: Modelling and prediction of global non-communicable diseases publication-title: BMC Public Health contributor: fullname: Wang, Y; Wang, J. – volume: 28 start-page: 105 issue: 2 year: 2002 end-page: 107 article-title: Are we doing a good job: PRISM, PIM and all that publication-title: Intensive Care Med. contributor: fullname: Shann, F. – volume: 31 start-page: 84 issue: 1 year: 2014 end-page: 87 article-title: Gases en sangre de arteria umbilical de neonatos a término en altura [Umbilical artery blood gases of term neonates at altitude] publication-title: Rev Peru Med Exp Salud Publica contributor: fullname: Villamonte, W; 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Title | Escala “Pediatric Index Mortality 3” (PIM3) como predictor de mortalidad en unidades de cuidado intensivo pediátrico ubicadas a gran altitud |
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