Use of Schirmer strips and conjunctival swabs for virus detection on the ocular surface of adults: a scoping review

ABSTRACT Schirmer strips and conjunctival swabs are used in ophthalmology for the collection of tears and fluids. One of the biggest challenges during the COVID-19 pandemic has been accurate diagnosis and, in some cases, ocular manifestations are among the first symptoms. In this context, this study...

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Published inArquivos brasileiros de oftalmologia Vol. 86; no. 3; pp. 284 - 291
Main Authors Sabage, Luís Expedito, Mazzo, Alessandra, Sabage, Josmar, Olivo, Taylor Endrigo Toscano, Santos, Carlos Ferreira, Lourençone, Luiz Fernando Manzoni
Format Journal Article
LanguagePortuguese
Published Conselho Brasileiro de Oftalmologia 01.05.2023
Subjects
OPHTHALMOLOGY
Polymerase chain reaction/methods
Eye protein/analysis
Antígeno de superfície/isolamento & purificação
Conjunctiva
Specimen handling
Reação em cadeia da polimerase/métodos
Manifestações oculares
COVID-19
Proteína do olho/análise
Antigen, surface/isolation & purification
Túnica conjuntiva
Lágrimas
Tears
Manejo de espécimes
Eye manifestations
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Summary:ABSTRACT Schirmer strips and conjunctival swabs are used in ophthalmology for the collection of tears and fluids. One of the biggest challenges during the COVID-19 pandemic has been accurate diagnosis and, in some cases, ocular manifestations are among the first symptoms. In this context, this study aimed to collect evidence to support the use of Schirmer strips and conjunctival swabs as a method of sample collection for viral analysis. A literature search was conducted following the Scoping Review protocol defined by The Joanna Briggs Institute. Studies were analyzed regarding virus research, collection methods, and sample analysis. The findings support that viruses can be detected on the ocular surface through analysis of Schirmer strips and conjunctival swabs. However, additional studies with larger samples and time data are necessary to confirm these conclusions.
ISSN:1678-2925
DOI:10.5935/0004-2749.20230032