Influenza- and respiratory syncytial virus-associated adult mortality in Soweto : original article
Background. Influenza and respiratory syncytial virus (RSV) infections cause seasonal excess mortality and hospitalisation in adults (particularly the elderly) in high-income countries. Little information exists on the impact of these infections on adults in Africa. Objectives. To estimate influenza...
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Published in | South African medical journal Vol. 99; no. 10; pp. 750 - 754 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Health and Medical Publishing Group (HMPG)
01.10.2009
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Online Access | Get full text |
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Summary: | Background. Influenza and respiratory syncytial virus (RSV) infections cause seasonal excess mortality and hospitalisation in adults (particularly the elderly) in high-income countries. Little information exists on the impact of these infections on adults in Africa. Objectives. To estimate influenza- and RSV-related adult mortality, stratified by age and hospitalisation in Soweto. Study design. A retrospective hospital-based study in Soweto from 1997 to 1999 to estimate influenza- and RSV-related excess all-cause deaths and hospitalisation using a rate-difference method. The study was based on influenza seasons of varying severity, provided by surveillance data. Results. Influenza seasons were significantly associated with excess mortality in adults across all 3 years, except for 18 - 64-year-olds in 1998. Excess mortality was highest in those ≥65 years of age : 82.8/100 000 population in the mild 1997 season and 220.9/100 000 in the severe 1998 season. Influenza significantly increased adult medical hospitalisation in the severe 1998 season alone. RSV did not significantly affect mortality or hospitalisation. Conclusion. Influenza-related mortality was substantial and disproportionately affected the elderly. Influenza vaccination for the elderly warrants consideration. The RSV-related burden was not significantly increased but merits observation over a longer period. |
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ISSN: | 0256-9574 2078-5135 |