A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review
Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pit...
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Published in | South African journal of obstetrics and gynaecology (1999) Vol. 18; no. 2; pp. 48 - 53 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Health and Medical Publishing Group (HMPG)
01.01.2012
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Online Access | Get full text |
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Abstract | Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation. |
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AbstractList | Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation. |
Author | Kruger, T.F. Botha, M.H. |
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Title | A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review |
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