A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review

Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pit...

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Bibliographic Details
Published inSouth African journal of obstetrics and gynaecology (1999) Vol. 18; no. 2; pp. 48 - 53
Main Authors Kruger, T.F., Botha, M.H.
Format Journal Article
LanguageEnglish
Published Health and Medical Publishing Group (HMPG) 01.01.2012
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Summary:Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation.
ISSN:0038-2329
2305-8862