Polyarteritis nodosa : pathological and clinical features : with a report on seven cases

The common clinical and pathological features of polyarteritis nodosa are descriptionbed. Seven cases of polyarteritis nodosa are presented with the clinical and pathological findings. In three cases the diagnosis was only made at autopsy. The first case presented with nephritis and generalised musc...

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Bibliographic Details
Published inSouth African medical journal Vol. 23; no. 1; pp. 8 - 19
Main Author Selzer, G. & Horwitz, M.
Format Journal Article
LanguageEnglish
Published Health and Medical Publishing Group (HMPG) 01.01.1949
Subjects
Glomerulonephritis
Polyarteritis nodosa
Rheumatic fever
Subcutaneous nodules
Vascular lesions
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Summary:The common clinical and pathological features of polyarteritis nodosa are descriptionbed. Seven cases of polyarteritis nodosa are presented with the clinical and pathological findings. In three cases the diagnosis was only made at autopsy. The first case presented with nephritis and generalised muscular tenderness; the second with mitral stenosis, pleural effusion and mental disturbances; the third as an acute abdominal emergency with massive retroperitoneal haemorrhage. In four cases the diagnosis was made during life. Two cases had typical clinical features and the diagnosis was confirmed by muscle biopsy. One case presented as an acute cholecystitis and the diagnosis was made on microscopy of the gall bladder. The fourth case presented with multiple arterial occlusions. The etiology is discussed and the probable allergic basis is stressed. Attention is drawn to the relationship between polyarteritis nodosa, rheumatic -fever and glomerulonephritis.
ISSN:0256-9574
2078-5135