A regio- and stereoselective HeckMatsuda process for construction of -aryl allylsulfonyl fluorides

A highly efficient regio- and stereoselective HeckMatsuda method was developed employing aryl diazoniums and allylsulfonyl fluorides for the construction of a class of novel -aryl allylsulfonyl fluorides in the presence of Pd(OAc) 2 and PPh 3 . The method features excellent regio- and stereoselectiv...

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Bibliographic Details
Published inRSC advances Vol. 12; no. 3; pp. 1942 - 1945
Main Authors Qin, Hao-Yong, Gui, Houying, Zhang, Zai-Wei, Shu, Tao, Qin, Hua-Li
Format Journal Article
Published 04.07.2022
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Summary:A highly efficient regio- and stereoselective HeckMatsuda method was developed employing aryl diazoniums and allylsulfonyl fluorides for the construction of a class of novel -aryl allylsulfonyl fluorides in the presence of Pd(OAc) 2 and PPh 3 . The method features excellent regio- and stereoselectivity (up to 100% E -selectivity), broad substrate scope and mild reaction conditions. Further application of -aryl allylsulfonyl fluoride in SuFEx reactions was achieved to provide their corresponding sulfonates and sulfonamides in excellent yields. A HeckMatsuda reaction of aryl diazoniums with allylsulfonyl fluorides for the construction of -aryl allylsulfonyl fluorides was developed.
Bibliography:https://doi.org/10.1039/d2ra03733e
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ISSN:2046-2069
DOI:10.1039/d2ra03733e