Asymmetric synthesis of planar-chiral macrocycles organocatalyzed enantioselective macrocyclization

A novel enantioselective macrocyclization method has been developed for the asymmetric synthesis of planar-chiral macrocycles through chiral phosphoric acid-catalyzed intramolecular addition of the hydroxy group with the allenamide moiety. A series of planar-chiral macrocycles bearing various ring s...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 58; no. 52; pp. 7293 - 7296
Main Authors Yu, Shaoze, Shen, Guosong, He, Faqian, Yang, Xiaoyu
Format Journal Article
Published 28.06.2022
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