Efficient visible light mediated synthesis of quinolin-2(1)-ones from quinoline -oxides
Quinolin-2(1 H )-ones are one of the important classes of compounds due to their prevalence in natural products and in pharmacologically useful compounds. Here we present an unconventional and hitherto unknown photocatalytic approach to their synthesis from easily available quinoline- N -oxides. Thi...
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| Published in | Green chemistry : an international journal and green chemistry resource : GC Vol. 23; no. 14; pp. 549 - 555 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Published |
21.07.2021
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| Online Access | Get full text |
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| Summary: | Quinolin-2(1
H
)-ones are one of the important classes of compounds due to their prevalence in natural products and in pharmacologically useful compounds. Here we present an unconventional and hitherto unknown photocatalytic approach to their synthesis from easily available quinoline-
N
-oxides. This reagent free highly atom economical photocatalytic method, with low catalyst loading, high yield and no undesirable by-product, provides an efficient greener alternative to all conventional synthesis reported to date. The robustness of the methodology has been successfully demonstrated with easy scaling up to the gram scale.
Quinolin-2(1
H
)-ones are prevalent in natural products and pharmacologically useful compounds. Here we present an unconventional and hitherto unknown photocatalytic approach to their synthesis from easily available quinoline-
N
-oxides. |
|---|---|
| Bibliography: | 1 13 C NMR spectra of products. See DOI Electronic supplementary information (ESI) available: General information, characterization data, and copies of H and 10.1039/d1gc01460a |
| ISSN: | 1463-9262 1463-9270 |
| DOI: | 10.1039/d1gc01460a |