Additive- and column-free synthesis of rigid bis-coumarins as fluorescent dyes for G-quadruplex sensing disaggregation-induced emission
A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and column-free, providing a facile and environment-friendly way to prepare fluorophores. The prepared novel fluorescent bis-coumarins exhibit f...
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| Published in | Chemical communications (Cambridge, England) Vol. 56; no. 5; pp. 687 - 6873 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
23.06.2020
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| Online Access | Get full text |
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| Abstract | A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and column-free, providing a facile and environment-friendly way to prepare fluorophores. The prepared novel fluorescent bis-coumarins exhibit favorable photophysical properties with good sensitivity and selectivity towards G-quadruplexes (G4s).
A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. |
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| AbstractList | A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and column-free, providing a facile and environment-friendly way to prepare fluorophores. The prepared novel fluorescent bis-coumarins exhibit favorable photophysical properties with good sensitivity and selectivity towards G-quadruplexes (G4s).
A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. |
| Author | Yu, Xiao-Qi He, Hui-Zi Li, Kun Chen, Shan-Yong Feng, Mei-Lin Yu, Kang-Kang Lu, Pei-Long |
| AuthorAffiliation | Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University |
| AuthorAffiliation_xml | – name: Key Laboratory of Green Chemistry and Technology of Ministry of Education – name: Sichuan University – name: College of Chemistry |
| Author_xml | – sequence: 1 givenname: Hui-Zi surname: He fullname: He, Hui-Zi – sequence: 2 givenname: Kun surname: Li fullname: Li, Kun – sequence: 3 givenname: Kang-Kang surname: Yu fullname: Yu, Kang-Kang – sequence: 4 givenname: Pei-Long surname: Lu fullname: Lu, Pei-Long – sequence: 5 givenname: Mei-Lin surname: Feng fullname: Feng, Mei-Lin – sequence: 6 givenname: Shan-Yong surname: Chen fullname: Chen, Shan-Yong – sequence: 7 givenname: Xiao-Qi surname: Yu fullname: Yu, Xiao-Qi |
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| DOI | 10.1039/d0cc01437k |
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| Notes | 10.1039/d0cc01437k 1 H NMR and For ESI and crystallographic data in CIF or other electronic format see DOI 13 C NMR), photophysical data for the corresponding products and G4 sensing experiments. CCDC 1968182 Electronic supplementary information (ESI) available: General experimental procedures and spectroscopic data |
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| Snippet | A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and... |
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| Title | Additive- and column-free synthesis of rigid bis-coumarins as fluorescent dyes for G-quadruplex sensing disaggregation-induced emission |
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