Additive- and column-free synthesis of rigid bis-coumarins as fluorescent dyes for G-quadruplex sensing disaggregation-induced emission

A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and column-free, providing a facile and environment-friendly way to prepare fluorophores. The prepared novel fluorescent bis-coumarins exhibit f...

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 56; no. 5; pp. 687 - 6873
Main Authors He, Hui-Zi, Li, Kun, Yu, Kang-Kang, Lu, Pei-Long, Feng, Mei-Lin, Chen, Shan-Yong, Yu, Xiao-Qi
Format Journal Article
LanguageEnglish
Published 23.06.2020
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Summary:A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed. This procedure is additive- and column-free, providing a facile and environment-friendly way to prepare fluorophores. The prepared novel fluorescent bis-coumarins exhibit favorable photophysical properties with good sensitivity and selectivity towards G-quadruplexes (G4s). A novel and efficient method to synthesize rigid bis-coumarins based on the dimerization of coumarinyl aldehydes was developed.
Bibliography:10.1039/d0cc01437k
1
H NMR and
For ESI and crystallographic data in CIF or other electronic format see DOI
13
C NMR), photophysical data for the corresponding products and G4 sensing experiments. CCDC
1968182
Electronic supplementary information (ESI) available: General experimental procedures and spectroscopic data
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc01437k