Preparation, characterization, and use of novel Cu@FeO MNPs in the synthesis of tetrahydrobenzimidazo[2,1-]quinazolin-1(2)-ones and 2-indazolo[2,1-]phthalazine-triones under solvent-free conditions

• Published in: RSC advances Vol. 9; no. 26; pp. 1561 - 1572
• Main Authors: Jiang, Lilin, Druzhinin, Zumrat
• Format: Journal Article
• Published: 14.05.2019
• ISSN: 2046-2069
• DOI: 10.1039/c9ra01509d

Cu@Fe 3 O 4 MNPs as novel nanomagnetic reagents were prepared to investigate their catalytic behavior in the preparation of tetrahydrobenzimidazo[2,1- b ]quinazolin-1(2 H )-ones, as important biologically active compounds. Then, characterization of the synthesized nanoparticles was performed using different methods including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) analysis, thermogravimetric analysis (TGA), vibrating sample magnetometer (VSM), energy dispersive X-ray (EDX), and scanning electron microscopy (SEM). All reactions were performed with small amounts of the Cu@Fe 3 O 4 MNPs under solvent-free conditions. After completion of the reaction, because of the magnetic nature of the nanocatalyst, they could be simply separated with an external magnet and easily reused with no considerable decrease in the catalytic behavior even after seven runs. Cu@Fe 3 O 4 MNPs as novel nanomagnetic reagents were prepared to investigate their catalytic behavior in the preparation of tetrahydrobenzimidazo[2,1- b ]quinazolin-1(2 H )-ones, as important biologically active compounds.