Free-standing three-dimensional hollow bacterial cellulose structures with controlled geometry via patterned superhydrophobic-hydrophilic surfacesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sm00112j
Bacteria can produce cellulose, one of the most abundant biopolymer on earth, and emerge as an interesting candidate to fabricate advanced materials. Cellulose produced by Komagataeibacter Xylinus , a bacterial strain, is a pure water insoluble biopolymer, without hemicellulose or lignin. Bacterial...
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Main Authors | , , , , , |
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Format | Journal Article |
Language | English |
Published |
16.05.2018
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Online Access | Get full text |
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Summary: | Bacteria can produce cellulose, one of the most abundant biopolymer on earth, and emerge as an interesting candidate to fabricate advanced materials. Cellulose produced by
Komagataeibacter Xylinus
, a bacterial strain, is a pure water insoluble biopolymer, without hemicellulose or lignin. Bacterial cellulose (BC) exhibits a nanofibrous porous network microstructure with high strength, low density and high biocompatibility and it has been proposed as cell scaffold and wound healing material. The formation of three dimensional (3D) cellulose self-standing structures is not simple. It either involves complex multi-step synthetic procedures or uses chemical methods to dissolve cellulose and remold it. Here we present an
in situ
single-step method to produce self-standing 3D-BC structures with controllable wall thickness, size and geometry in a reproducible manner. Parameters such as hydrophobicity of the surfaces, volume of the inoculum and time of culture define the resulting 3D-BC structures. Hollow spheres and convex domes can be easily obtained by changing the surface wettability. The potential of these structures as a 3D cell scaffold is exemplified supporting the growth of mouse embryonic stem cells within a hollow spherical BC structure, indicating its biocompatibility and future prospective.
Biosynthesis of multiple shapes of 3D self-standing BC structures in a static one-step process to fabricate advanced materials. |
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Bibliography: | 10.1039/c8sm00112j Electronic supplementary information (ESI) available. See DOI |
ISSN: | 1744-683X 1744-6848 |
DOI: | 10.1039/c8sm00112j |