An aryne triggered ring-opening fluorination of cyclic thioethers with potassium fluorideElectronic supplementary information (ESI) available. See DOI: 10.1039/c8cc03766c

Herein, we report an aryne triggered ring-opening fluorination protocol of a great variety of saturated sulfur heterocycles. A key factor for the success is the identification of a suitable mediator. Compared to previous methods, this transition-metal free protocol employs low-cost potassium fluorid...

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Bibliographic Details
Main Authors Fan, Rong, Liu, Binbin, Zheng, Tianyu, Xu, Kun, Tan, Chen, Zeng, Tianlong, Su, Shuaisong, Tan, Jiajing
Format Journal Article
Published 21.06.2018
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Summary:Herein, we report an aryne triggered ring-opening fluorination protocol of a great variety of saturated sulfur heterocycles. A key factor for the success is the identification of a suitable mediator. Compared to previous methods, this transition-metal free protocol employs low-cost potassium fluoride as the fluorine source. The operational simplicity and mild reaction conditions allow for the rapid synthesis of a wide range of aliphatic fluoride compounds in good yields. Herein, we report an aryne triggered ring-opening fluorination protocol of a great variety of saturated sulfur heterocycles.
Bibliography:10.1039/c8cc03766c
Electronic supplementary information (ESI) available. See DOI
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc03766c