Light-switchable nanoparticles based on amphiphilic diblock, triblock and heterograft polyoxazolineElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra07094b
Photo-active nanoparticles (NP D , NP T , NP H ) were elaborated in water from amphiphilic diblock (D), triblock (T) and heterograft (H) copolymers based on a chromatic unit, coumarin, linked to an alkyl chain and a hydrophilic polyoxazoline chain. Under UV-exposure, for graft copolymers, the coumar...
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Main Authors | , , , , |
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Format | Journal Article |
Language | English |
Published |
04.09.2017
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Online Access | Get full text |
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Summary: | Photo-active nanoparticles (NP
D
, NP
T
, NP
H
) were elaborated in water from amphiphilic diblock (D), triblock (T) and heterograft (H) copolymers based on a chromatic unit, coumarin, linked to an alkyl chain and a hydrophilic polyoxazoline chain. Under UV-exposure, for graft copolymers, the coumarin moieties crosslink the nanoparticle core (NP
Hx
) while a simple chain by chain dimerization happens with linear diblock and triblock copolymers (NP
Dx
and NP
T
). The self-assembly of these copolymers was examined as well as the UV-activity and UV-reversibility of the corresponding NPs by UV spectroscopy. Their stability under light exposure and temperature was also monitored by dynamic light scattering (DLS). Finally, the loading of a lipophilic fluorescent probe (Nile red) into the NP core was evaluated by fluorescence emission. All these data illustrate the tunable size, UV-activity, stability and loading efficiency of the NPs by the starting macromolecular architecture of the amphiphilic copolymers. Triblock copolymers seem to be a promising tool for switchable NPs characterized by two opposite states: NPs alternatively with and without a photo-dimerized core.
Photo-active nanoparticles (NP
D
, NP
T
, NP
H
) were elaborated in water from amphiphilic diblock (D), triblock (T) and heterograft (H) copolymers based on a chromatic unit, coumarin, linked to an alkyl chain and a hydrophilic polyoxazoline chain. |
---|---|
Bibliography: | 10.1039/c7ra07094b Electronic supplementary information (ESI) available. See DOI |
ISSN: | 2046-2069 |
DOI: | 10.1039/c7ra07094b |