Synthesis and insecticidal assessment of some innovative heterocycles incorporating a thiadiazole moiety against the cotton leafworm, Spodoptera littoralisElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ra06087d

• Main Authors: Fadda, Ahmed A, El Salam, M. Abd, Tawfik, Eman H, Anwar, E. M, Etman, H. A
• Format: Journal Article
• Language: English
• Published: 15.08.2017
• ISSN: 2046-2069
• DOI: 10.1039/c7ra06087d

New 2-cyano- N -(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide ( 1 ) was utilized as a versatile precursor for the synthesis of various heterocycles, such as pyrrole, pyridine, coumarin, thiazole, pyrido[2′,3′:3,4]pyrazolo[5,1- c ]triazine, triazolo[5,1- c ]triazine, aminopyrazole, thiophene, 1,3-dithiolane, triazolo[1,5- a ]pyrimidine and benzo[ d ]imidazole derivatives. The newly synthesized compounds were identified by IR, MS, 1 H NMR, 13 C NMR, DEPT, H-H COSY, HMBC, and HSQC. Representative compounds of the synthesized products were examined and estimated as insecticidal agents against the cotton leafworm, Spodoptera littoralis . A new 2-cyano- N -(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide was utilized as a versatile precursor for the synthesis of various heterocycles.