Lipoic acid based core cross-linked micelles for multivalent platforms: design, synthesis and application in bio-imaging and drug deliveryElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob00927e

Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water. The presence of numerous disulfides accumulated in the core makes the micelles readily cross-linked to achieve the establishment of core cross-linked micelles (CCMs). Thanks to the inherent biocompatibility,...

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Bibliographic Details
Main Authors Huang, Jingsheng, Wu, Fang, Yu, Yunlong, Huang, Haolong, Zhang, Shiyong, You, Jingsong
Format Journal Article
LanguageEnglish
Published 07.06.2017
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Summary:Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water. The presence of numerous disulfides accumulated in the core makes the micelles readily cross-linked to achieve the establishment of core cross-linked micelles (CCMs). Thanks to the inherent biocompatibility, the resulting lipoic acid based CCMs (LA-CCMs) are good multivalent platforms for biomedical applications. Natural lipoic acid derived small-molecule amphiphiles self-assemble into micelles in water.
Bibliography:10.1039/c7ob00927e
Electronic supplementary information (ESI) available. See DOI
ISSN:1477-0520
1477-0539
DOI:10.1039/c7ob00927e